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\n\u6700\u3082\u591a\u3044\u75c7\u72b6\u306f\u76ae\u819a\u969c\u5bb3\u3067\u3001\u304b\u3086\u3044\u767a\u75b9\uff08\u307b\u3063\u3057\u3093\uff09\u304c\u51fa\u305f\u308a\u3001\u30ab\u30b5\u30ab\u30b5\u306b\u306a\u3063\u3066\u786c\u304f\u306a\u308a\u3001\u90e8\u5206\u7684\u306b\u8131\u6bdb\u3001\u8131\u8272\u3057\u305f\u308a\u3057\u307e\u3059\u3002\u307e\u305f\u3001\u6d99\u817a\u306b\u640d\u50b7\u3092\u53d7\u3051\u3066\u6d99\u306e\u91cf\u304c\u6e1b\u308b\u305f\u3081\u3001\u773c\u7403\u306e\u8868\u9762\uff08\u7d50\u819c\u3068\u3044\u3044\u307e\u3059\uff09\u304c\u4e7e\u71e5\u3057\u3066\u75db\u307f\u3084\u8996\u529b\u969c\u5bb3\u3092\u6765\u3059\u3001\u3044\u308f\u3086\u308b\u30c9\u30e9\u30a4\u30a2\u30a4\u3084\u76ee\u306e\u523a\u6fc0\u611f\u304c\u73fe\u308c\u307e\u3059\u3002\u53e3\u306e\u4e2d\u306e\u553e\u6db2\u817a\u3082\u4fb5\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u304f\u3001\u98df\u4e8b\u306e\u3068\u304d\u306b\u3057\u307f\u305f\u308a\u3057\u307e\u3059\u3002\u98df\u9053\u306b\u75c5\u5909\u304c\u3042\u308b\u3068\u3001\u98f2\u307f\u8fbc\u3080\u306e\u304c\u56f0\u96e3\u306b\u306a\u308a\u307e\u3059\u3002\u809d\u81d3\u306e\u969c\u5bb3\u304b\u3089\u3001\u9ec4\u75b8\u3084\u809d\u6a5f\u80fd\u691c\u67fb\u7d50\u679c\u306e\u7570\u5e38\u304c\u307f\u3089\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u80c3\u7c98\u819c\u3084\u8178\u306e\u7c98\u6db2\u5206\u6ccc\u817a\uff08\u3076\u3093\u3074\u305b\u3093\uff09\u304c\u50b7\u5bb3\u3055\u308c\u308b\u3068\u3001\u9069\u5207\u306a\u6804\u990a\u5438\u53ce\u529b\u304c\u59a8\u3052\u3089\u308c\u3066\u80f8\u713c\u3051\u3001\u80c3\u75db\u3001\u8179\u75db\u3001\u4f53\u91cd\u6e1b\u5c11\u7b49\u304c\u8d77\u3053\u308a\u307e\u3059\u3002\u7b4b\u819c\u304c\u786c\u304f\u306a\u3063\u305f\u308a\u8171\u304c\u840e\u7e2e\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u95a2\u7bc0\u306e\u66f2\u3052\u4f38\u3070\u3057\u304c\u56f0\u96e3\u306b\u306a\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u80ba\u304c\u786c\u304f\u306a\u308b\u3068\u3001\u5598\u606f\u306e\u3088\u3046\u306a\u5598\u9cf4\uff08\u305c\u3093\u3081\u3044\uff09\u97f3\u304c\u805e\u3053\u3048\u305f\u308a\u3001\u547c\u5438\u304c\u3046\u307e\u304f\u3067\u304d\u306a\u304f\u306a\u3063\u3066\u606f\u82e6\u3057\u3055\u3092\u611f\u3058\u305f\u308a\u3057\u307e\u3059\u3002\u3072\u3069\u3044\u5834\u5408\u306b\u306f\u3001\u8840\u6db2\u4e2d\u306e\u9178\u7d20\u6fc3\u5ea6\u304c\u4f4e\u4e0b\u3057\u3066\u52d5\u3051\u306a\u304f\u306a\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u3089\u4ee5\u5916\u306e\u81d3\u5668\u306b\u3082\u3001\u6162\u6027GVHD\u306b\u95a2\u9023\u3059\u308b\u969c\u5bb3\u304c\u51fa\u73fe\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3044\u305a\u308c\u306e\u75c7\u72b6\u3082\u500b\u4eba\u5dee\u304c\u3042\u308a\u3001\u4eba\u306b\u3088\u3063\u3066\u3069\u306e\u3088\u3046\u306a\u75c7\u72b6\u304c\u3001\u3069\u306e\u7a0b\u5ea6\u306e\u91cd\u75c7\u5ea6\u3067\u51fa\u73fe\u3059\u308b\u304b\u306f\u3055\u307e\u3056\u307e\u3067\u3059\u3002<\/p>\n

\uff11\uff17\uff0e\u6162\u6027\u79fb\u690d\u7247\u5bfe\u5bbf\u4e3b\u75c5\uff08\u6162\u6027GVHD\uff09\u306e\u6cbb\u7642\u9069\u5fdc
\n\u6162\u6027GVHD\u304c\u3055\u307b\u3069\u91cd\u75c7\u3067\u306a\u3044\u5834\u5408\u3001\u4f8b\u3048\u3070\u75c7\u72b6\u304c\uff11\uff5e\uff12\u81d3\u5668\u3060\u3051\u306b\u3042\u3063\u3066\u75c7\u72b6\u304c\u3055\u307b\u3069\u5f37\u304f\u306a\u3044\u5834\u5408\u306f\u3001\u539f\u5247\u3068\u3057\u3066\u5916\u7528\u85ac\u306a\u3069\u306e\u5c40\u6240\u7642\u6cd5\u3092\u9078\u629e\u3057\u307e\u3059\u3002\u5185\u670d\u85ac\u306a\u3069\u3092\u7528\u3044\u305f\u5168\u8eab\u6cbb\u7642\u306f\u3001\u75c7\u72b6\u304c\uff13\u81d3\u5668\u4ee5\u4e0a\u306b\u53ca\u3076\u5834\u5408\u3001\u307e\u305f\u306f\uff11\u81d3\u5668\u306e\u307f\u3067\u3042\u3063\u3066\u3082\u75c7\u72b6\u304c\u5f37\u3044\u5834\u5408\u306b\u884c\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3069\u306e\u6cbb\u7642\u3092\u9078\u629e\u3059\u308b\u304b\u306f\u53b3\u5bc6\u306a\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u7a2e\u3005\u306e\u8981\u4ef6\u3092\u8e0f\u307e\u3048\u3066\u60a3\u8005\u3055\u3093\u3054\u3068\u306b\u6c7a\u5b9a\u3057\u307e\u3059\u3002\u79fb\u690d\u7247\u5bfe\u767d\u8840\u75c5\uff08GVT\uff09\u52b9\u679c\u3092\u751f\u304b\u3057\u305f\u3044\u3068\u304d\u3001\u3042\u308b\u3044\u306f\u611f\u67d3\u75c7\u3092\u5408\u4f75\u3057\u3066\u3044\u308b\u3068\u304d\u306f\u3001\u5168\u8eab\u6cbb\u7642\u3092\u6d88\u6975\u7684\u306b\u8003\u3048\u307e\u3059\u3002\u9006\u306b\u3001\u539f\u75c5\u304c\u518d\u751f\u4e0d\u826f\u6027\u8ca7\u8840\u306e\u3088\u3046\u306b\u304c\u3093\u3067\u306f\u306a\u3044\u75be\u60a3\u306e\u5834\u5408\u3084\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306aGVHD\u306e\u4e88\u5f8c\u4e0d\u826f\u56e0\u5b50\u304c\u3042\u308b\u5834\u5408\u306f\u3001\u5168\u8eab\u6cbb\u7642\u3092\u6bd4\u8f03\u7684\u7a4d\u6975\u7684\u306b\u8003\u616e\u3057\u307e\u3059\u3002<\/p>\n

\u6162\u6027GVHD\u8a3a\u65ad\u6642\u306e\u75c7\u72b6\u3084\u691c\u67fb\u6240\u898b\u306b\u3088\u308a\u3001\u305d\u306e\u5f8c\u306e\u7d4c\u904e\u3092\u63a8\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u3053\u308c\u3092\u4e88\u5f8c\u63a8\u5b9a\u56e0\u5b50\u3068\u3044\u3044\u3001\u73fe\u5728\u307e\u3067\u306b\u7a2e\u3005\u306e\u56e0\u5b50\u304c\u540c\u5b9a\u3055\u308c\u3001progressive\u578b\u306e\u767a\u75c7\u5f62\u5f0f\u3001\u8840\u5c0f\u677f\u6e1b\u5c11\uff0810\u4e07\u4ee5\u4e0b\uff09\u3001\u5e83\u7bc4\u306a\u76ae\u819a\u75c5\u5909\u3001\u4e0b\u75e2\u3084\u4f53\u91cd\u6e1b\u5c11\u306a\u3069\u306e\u6d88\u5316\u7ba1\u969c\u5bb3\u3001\u4e0d\u826f\u306a\u5168\u8eab\u72b6\u614b\u304c\u3042\u3052\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\uff11\uff18\uff0e\u6162\u6027\u79fb\u690d\u7247\u5bfe\u5bbf\u4e3b\u75c5\uff08\u6162\u6027GVHD\uff09\u306b\u5bfe\u3059\u308b\u5c40\u6240\u7642\u6cd5\u3001\u652f\u6301\u7642\u6cd5
\n\u76ae\u819a\u3084\u53e3\u306e\u4e2d\u306e\u75c5\u5909\u306b\u5bfe\u3057\u3066\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u3084\u30bf\u30af\u30ed\u30ea\u30e0\u30b9\u3092\u542b\u3093\u3060\u5857\u308a\u85ac\uff08\u5916\u7528\u5264\uff09\u3001\u553e\u6db2\u6e1b\u5c11\u306b\u5bfe\u3059\u308b\u3046\u304c\u3044\u3084\u4eba\u5de5\u553e\u6db2\u3001\u30ac\u30e0\u306b\u3088\u308b\u523a\u6fc0\u304c\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u5916\u51fa\u6642\u306a\u3069\u306b\u3001\u76ae\u819a\u3092\u7d2b\u5916\u7dda\u304b\u3089\u9632\u8b77\u3059\u308b\u3053\u3068\u3082\u5927\u5207\u3067\u3059\u3002\u6d88\u5316\u7ba1\u5438\u53ce\u969c\u5bb3\u3068\u4f53\u91cd\u6e1b\u5c11\u306b\u5bfe\u3057\u3066\u306f\u3001\u81b5\uff08\u3059\u3044\uff09\u9175\u7d20\u88fd\u5264\u306e\u5185\u670d\u304c\u8a66\u307f\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u773c\u7403\u304c\u4e7e\u71e5\u3059\u308b\u3068\u3001\u611f\u67d3\u75c7\u3084\u89d2\u819c\u306e\u969c\u5bb3\u3092\u6765\u3057\u3066\u8996\u529b\u4f4e\u4e0b\u304c\u307f\u3089\u308c\u308b\u5834\u5408\u304c\u3042\u308b\u305f\u3081\u3001\u4eba\u5de5\u6d99\u6db2\u306e\u70b9\u773c\u3084\u6d99\u70b9\u9589\u9396\u8853\u304c\u884c\u308f\u308c\u307e\u3059\u3002\u7b4b\u819c\u708e\u3084\u76ae\u819a\u786c\u5316\u306b\u3088\u308a\u95a2\u7bc0\u306e\u52d5\u304d\u304c\u60aa\u304f\u306a\u308b\u3068\u65e5\u5e38\u751f\u6d3b\u306b\u652f\u969c\u304c\u751f\u3058\u308b\u306e\u3067\u3001\u305d\u306e\u9632\u6b62\u306e\u305f\u3081\u306e\u7406\u5b66\u7642\u6cd5\u304c\u6709\u7528\u3067\u3059\u3002\u9577\u671f\u9593\u306e\u30b9\u30c6\u30ed\u30a4\u30c9\u4f7f\u7528\u306b\u4f34\u3046\u526f\u4f5c\u7528\u5bfe\u7b56\u3068\u3057\u3066\u3001\u7cd6\u5c3f\u75c5\u3084\u8010\u7cd6\u80fd\u7570\u5e38\u306b\u5bfe\u3059\u308b\u98df\u4e8b\u30fb\u904b\u52d5\u7642\u6cd5\u3001\u9aa8\u7c97\u9b06\u75c7\uff08\u3053\u3064\u305d\u3057\u3087\u3046\u3057\u3087\u3046\uff09\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u304c\u884c\u308f\u308c\u307e\u3059\u3002\u9589\u585e\u6027\u7d30\u6c17\u7ba1\u652f\u708e\u306f\u6cbb\u7642\u304c\u96e3\u3057\u3044\u80ba\u306e\u5408\u4f75\u75c7\u3067\u3059\u3002\u91cd\u75c7\u306e\u5834\u5408\u3001\u65e5\u5e38\u751f\u6d3b\u306b\u3082\u652f\u969c\u304c\u751f\u3058\u308b\u307b\u3069\u8840\u6db2\u4e2d\u306e\u9178\u7d20\u6fc3\u5ea6\u306e\u4f4e\u4e0b\u304c\u8d77\u3053\u308b\u305f\u3081\u3001\u547c\u5438\u30ea\u30cf\u30d3\u30ea\u30c6\u30fc\u30b7\u30e7\u30f3\u3084\u5728\u5b85\u9178\u7d20\u7642\u6cd5\u304c\u884c\u308f\u308c\u308b\u5834\u5408\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n

\uff11\uff19\uff0e\u6162\u6027\u79fb\u690d\u7247\u5bfe\u5bbf\u4e3b\u75c5\uff08\u6162\u6027GVHD\uff09\u306b\u5bfe\u3059\u308b\u5168\u8eab\u7642\u6cd5
\n\u4e00\u822c\u7684\u306b\u7528\u3044\u3089\u308c\u3066\u3044\u308b\u65b9\u6cd5\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u5264\u3068\u30b7\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\u3084\u30bf\u30af\u30ed\u30ea\u30e0\u30b9\u306e\u4f75\u7528\u7642\u6cd5\u3067\u3059\u3002\u60a3\u8005\u3055\u3093\u306e\u4f53\u91cd\uff11kg\u3042\u305f\u308a\uff11mg\u3067\u30b9\u30c6\u30ed\u30a4\u30c9\u5264\u3092\u958b\u59cb\u3059\u308b\u3053\u3068\u304c\u6a19\u6e96\u7684\u3068\u8003\u3048\u3089\u308c\u3001\u75c7\u72b6\u306e\u6539\u5584\u304c\u307f\u3089\u308c\u308c\u3070\u5f90\u3005\u306b\u6295\u4e0e\u91cf\u3092\u6e1b\u3089\u3057\u3066\u3044\u304f\u3053\u3068\u304c\u4e00\u822c\u7684\u3067\u3059\u3002\u305f\u3060\u3001\u9069\u5207\u306a\u6295\u4e0e\u671f\u9593\u3084\u6e1b\u91cf\u901f\u5ea6\u306b\u95a2\u3057\u3066\u306f\u3001\u5b9a\u307e\u3063\u305f\u65b9\u6cd5\u304c\u77e5\u3089\u308c\u3066\u3044\u306a\u3044\u306e\u304c\u73fe\u72b6\u3067\u3059\u3002\u6e1b\u91cf\u306e\u6700\u7d42\u6bb5\u968e\u3067\u306f\u3001\u526f\u814e\u306e\u50cd\u304d\u304c\u60aa\u304f\u306a\u308b\u3053\u3068\u304c\u3042\u308b\u305f\u3081\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002\u305f\u3060\u3001\u4ee5\u4e0a\u306e\u85ac\u5264\u91cf\u3084\u6e1b\u91cf\u6cd5\u304c\u65e5\u672c\u4eba\u306e\u60a3\u8005\u3055\u3093\u306b\u3082\u9069\u5207\u304b\u3069\u3046\u304b\u306f\u4e0d\u660e\u306e\u305f\u3081\u3001\u60a3\u8005\u3055\u3093\u306e\u75c7\u72b6\u306a\u3069\u306b\u3088\u308a\u3001\u4ed6\u306e\u65b9\u6cd5\u3082\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u6cbb\u7642\u671f\u9593\u306b\u95a2\u3057\u3066\u3082\u8b70\u8ad6\u306e\u3042\u308b\u3068\u3053\u308d\u3067\u3001\u3059\u3079\u3066\u306e\u75c7\u72b6\u304c\u6d88\u5931\u3059\u308b\u307e\u3067\u7d9a\u884c\u3059\u3079\u304d\u304b\u5426\u304b\u306f\u3001\u6cbb\u7642\u306b\u4f34\u3046\u85ac\u5264\u306e\u526f\u4f5c\u7528\u3084\u611f\u67d3\u75c7\u306a\u3069\u5408\u4f75\u75c7\u3068\u306e\u30d0\u30e9\u30f3\u30b9\u3067\u6c7a\u3081\u3089\u308c\u307e\u3059\u3002\u6d99\u817a\u969c\u5bb3\u3084\u4e00\u90e8\u306e\u76ae\u819a\u30fb\u53e3\u8154\u75c5\u5909\u3001\u80ba\u306e\u6240\u898b\u306fGVHD\u304c\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3055\u308c\u3066\u3044\u3066\u3082\u6b8b\u5b58\u3059\u308b\u305f\u3081\u3001\u6cbb\u7642\u7d9a\u884c\u306e\u76ee\u5b89\u306b\u306f\u306a\u3089\u306a\u3044\u3068\u3044\u308f\u308c\u3066\u3044\u307e\u3059\u3002\u30b9\u30c6\u30ed\u30a4\u30c9\u5264\u306f\u3001\u3057\u3070\u3057\u3070\u9577\u671f\u4f7f\u7528\u304c\u5fc5\u8981\u3068\u306a\u308a\u307e\u3059\u3002\u4f75\u7528\u3059\u308b\u30b7\u30af\u30ed\u30b9\u30dd\u30ea\u30f3\u3084\u30bf\u30af\u30ed\u30ea\u30e0\u30b9\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u5264\u3092\u4e2d\u6b62\u3057\u305f\u5f8c\u306b\u6e1b\u91cf\u3059\u308b\u306e\u304c\u539f\u5247\u3067\u3059\u304c\u3001\u305d\u306e\u6295\u4e0e\u91cf\u306f\u5341\u5206\u306b\u306f\u691c\u8a0e\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n

\u3053\u3046\u3057\u305f\u30b9\u30c6\u30ed\u30a4\u30c9\u5264\u3092\u4e2d\u5fc3\u3068\u3059\u308b\u521d\u56de\u6cbb\u7642\u304c\u6210\u529f\u3057\u306a\u304b\u3063\u305f\u3068\u304d\u306b\u884c\u3046\u6cbb\u7642\u306e\u3053\u3068\u3092\u3001\u4e8c\u6b21\u6cbb\u7642\u3068\u3044\u3044\u307e\u3059\u3002\u4e8c\u6b21\u6cbb\u7642\u306f\u3001\u6a19\u6e96\u7684\u306a\u4e00\u6b21\u6cbb\u7642\u3067\u3042\u308b\u30b9\u30c6\u30ed\u30a4\u30c9\u5264\u3092\uff12\u9031\u9593\u6295\u4e0e\u3057\u3066\u3082\u5897\u60aa\u3059\u308b\u5834\u5408\u3001\u3042\u308b\u3044\u306f\uff14\uff5e\uff18\u9031\u9593\u6cbb\u7642\u3092\u7d99\u7d9a\u3057\u305f\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u6539\u5584\u3057\u306a\u3044\u5834\u5408\u306b\u884c\u3044\u307e\u3059\u3002\u5f8c\u8005\u306b\u306f\u3001\u30b9\u30c6\u30ed\u30a4\u30c9\u5264\u3092\u4f53\u91cd\u3042\u305f\u308a0.5mg\u672a\u6e80\u306b\u307e\u3067\u6e1b\u91cf\u3067\u304d\u306a\u3044\u5834\u5408\u3082\u542b\u307e\u308c\u307e\u3059\u3002\u4e8c\u6b21\u6cbb\u7642\u306f\u3001\u6bd4\u8f03\u7684\u8efd\u75c7\u306e\u5834\u5408\u306f\u7d4c\u53e3\u5264\u3067\u3042\u308b\u30df\u30b3\u30d5\u30a7\u30ce\u30fc\u30eb\u9178\u30e2\u30d5\u30a7\u30c1\u30eb\u3001\u30b7\u30ed\u30ea\u30e0\u30b9\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30af\u30ed\u30ed\u30ad\u30f3\u3001\u30b5\u30ea\u30c9\u30de\u30a4\u30c9\u7b49\u3001\u3088\u308a\u91cd\u75c7\u306a\u5834\u5408\u306f\u3001\u30d5\u30a9\u30c8\u30d5\u30a7\u30ec\u30fc\u30b7\u30b9\u3001\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3001\u30da\u30f3\u30c8\u30b9\u30bf\u30c1\u30f3\u3001\u9ad8\u7528\u91cf\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u30d1\u30eb\u30b9\u7642\u6cd5\u7b49\u304c\u3042\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u3044\u305a\u308c\u306e\u52b9\u679c\u3082\u5341\u5206\u3067\u306f\u306a\u3044\u3046\u3048\u306b\u3001\u308f\u304c\u56fd\u3067\u306f\u4f7f\u7528\u7d4c\u9a13\u304c\u4e4f\u3057\u304f\u3001\u307e\u305f\u4fdd\u967a\u9069\u7528\u5916\u306e\u6cbb\u7642\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n

\n\uff12\uff10\uff0e\u53c2\u8003\u6587\u732e
\n\u3088\u308a\u8a73\u3057\u3044\u60c5\u5831\u306b\u3064\u3044\u3066\u306f\u3001\u4ee5\u4e0b\u306e\u6587\u732e\u3092\u304a\u85a6\u3081\u3057\u307e\u3059\u3002 <\/p>\n

1) Ferrara, J. L.; Reddy, P. Pathophysiology of graft-versus-host disease. Seminars in hematology. 2006, vol. 43, p. 3-10.
\n2) Kanda, Y. et al. Effect of graft-versus-host disease on the outcome of bone marrow transplantation from an HLA-identical sibling donor using GVHD prophylaxis with cyclosporin A and methotrexate. Leukemia. 2004, vol. 18, p. 1013-1019.
\n3) Yanada, M. et al. Tacrolimus instead of cyclosporine used for prophylaxis against graft-versus-host disease improves outcome after hematopoietic stem cell transplantation from unrelated donors, but not from HLA-identical sibling donors: a nationwide survey conducted in Japan. Bone Marrow Transplantation. 2004, vol. 34, p. 331-337.
\n4) \u65e5\u672c\u9020\u8840\u7d30\u80de\u79fb\u690d\u5b66\u4f1a\u5168\u56fd\u30c7\u30fc\u30bf\u4e8b\u52d9\u5c40. \u5e73\u621016\u5e74\u5ea6\u5168\u56fd\u8abf\u67fb\u5831\u544a\u66f8. 2005, http:\/\/www.jshct.com\/report_2004\/index.html, (\u53c2\u7167 2006-10-01).
\n5) \u65e5\u672c\u9020\u8840\u7d30\u80de\u79fb\u690d\u5b66\u4f1a. \u9020\u8840\u7d30\u80de\u79fb\u690d\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3: GVHD\u306e\u8a3a\u65ad\u3068\u6cbb\u7642\u306b\u95a2\u3059\u308b\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3. JSHCT monograph, 1999, vol. 1, http:\/\/www.jshct.com\/guide_pdf\/1999gvhv2.pdf, (\u53c2\u7167 2006-10-01).
\n6) Nishida, T. et al. Intestinal thrombotic microangiopathy after allogeneic bone marrow transplantation: a clinical imitator of acute enteric graft-versus-host disease. Bone Marrow Transplantation. 2004,\u3000vol. 33, p. 1143-1150.
\n7) Filipovich, A. H. et al. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. Diagnosis and Staging Working Group Report. Biology of blood and marrow transplantation. 2005, vol. 11, p. 945-956. <\/p>\n","protected":false},"excerpt":{"rendered":"

\uff11\uff13\uff0e\u6162\u6027\u79fb\u690d\u7247\u5bfe\u5bbf\u4e3b\u75c5\uff08\u6162\u6027GVHD\uff09\u3068\u306f \u6162\u6027GVHD\u306f\u3001\u79fb\u690d\u7247\u306e\u4e2d\u306b\u3042\u308b\u5e79\u7d30\u80de\u304c\u60a3\u8005\u3055\u3093\u306b\u751f\u7740\u3057\u305f\u5f8c\u306b\u3001\u60a3\u8005\u3055\u3093\u306e\u4f53\u306e\u4e2d\u3067\u65b0\u305f\u306b\u3064\u304f\u3089\u308c\u305f\uff34\u7d30\u80de\u304c\u5f15\u304d\u8d77\u3053\u3059\u514d\u75ab\u53cd\u5fdc\u306b\u3088\u308b\u3082\u306e\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u901a\u5e38\u3001\u79fb\u690d\u5f8c\u7d04100 … <\/p>\n

“GVHD \u305d\u306e\uff12 \u6162\u6027\u79fb\u690d\u7247\u5bfe\u5bbf\u4e3b\u75c5\uff08\u6162\u6027GVHD\uff09” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-113","post","type-post","status-publish","format-standard","hentry","category-9"],"_links":{"self":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts\/113","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=113"}],"version-history":[{"count":0,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts\/113\/revisions"}],"wp:attachment":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=113"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=113"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=113"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}