{"id":118,"date":"2008-06-19T20:25:59","date_gmt":"2008-06-19T11:25:59","guid":{"rendered":"http:\/\/haruko.km2m.net\/2008\/06\/19\/g-csf-%e3%81%af%e5%ae%89%e5%85%a8%ef%bc%9f\/"},"modified":"2008-06-19T20:25:59","modified_gmt":"2008-06-19T11:25:59","slug":"g-csf-%e3%81%af%e5%ae%89%e5%85%a8%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/haruko.km2m.net\/?p=118","title":{"rendered":"G-CSF \u306f\u5b89\u5168\uff1f"},"content":{"rendered":"

G-CSF \u306f\u5b89\u5168\uff1f<\/p>\n

\u30002000\u5e74\uff14\u6708\u306b\u8a8d\u53ef\u3055\u308c\u305f\u672b\u68a2\u8840\u5e79\u7d30\u80de\u79fb\u690d\u3067\u306fG-CSF\uff08\u9846\u7c92\u7403\u30b3\u30ed\u30cb\u30fc\u523a\u6fc0\u56e0\u5b50\uff09\u3092\u5065\u5eb7\u306a\u30c9\u30ca\u30fc\u306b\u6ce8\u5c04\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u306eG-CSF\u306e\u5b89\u5168\u6027\u306b\u3064\u3044\u3066\u306f\u4ee5\u524d\u3082\u8ff0\u3079\u307e\u3057\u305f\uff08\u9e7f\u5150\u5cf6\u5e02\u533b\u5831\u3000\u7b2c42\u5dfb\u7b2c10\u53f7\uff0c\u901a\u5dfb500\u53f7\uff0c74\uff0d75\u30da\u30fc\u30b8\uff0c2003\u5e74\uff09\u3002\u672c\u5f53\u306bG-CSF\u306f\u5065\u5eb7\u306a\u4eba\u306b\u3068\u3063\u3066\u5b89\u5168\u3067\u3057\u3087\u3046\u304b\uff1f \u6700\u65b0\u306e\u60c5\u5831\u304b\u3089\u518d\u5ea6\u691c\u8a3c\u3057\u3066\u307f\u307e\u3059\u3002
\n\u3000G-CSF\u6295\u4e0e\u306b\u4ee5\u4e0b\u306e\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002\uff11\uff0e\u672b\u68a2\u8840\u5e79\u7d30\u80de\u63a1\u53d6\u306e\u76ee\u7684\u3067\u5065\u5eb7\u4eba\u306b\u6295\u4e0e\u3002\uff12\uff0e\u6297\u304c\u3093\u5264\u6295\u4e0e\u5f8c\u307e\u305f\u306f\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d\u5f8c\u306e\u597d\u4e2d\u7403\u56de\u5fa9\u4fc3\u9032\u306e\u305f\u3081\u3002\uff13\uff0e\u6297\u304c\u3093\u5264\u306e\u52b9\u679c\u3092\u5897\u5f37\u3059\u308b\u3002<\/p>\n

\n\u767d\u8840\u75c5\u3092\u8a98\u5c0e\u3059\u308b\u53ef\u80fd\u6027\u306f\uff1f<\/p>\n

\u3000\u307e\u305a\uff0c\uff11\uff0e\u306e\u69d8\u306a\u5834\u5408\uff0c\u5065\u5eb7\u306a\u4eba\u306bG-CSF\u3092\u6295\u4e0e\u3057\u3066\u76f4\u3050\u306b\u767d\u8840\u75c5\u3092\u3072\u304d\u304a\u3053\u3059\u3053\u3068\u306fin vitro\u3067\u306f\u5b8c\u5168\u306b\u5426\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u554f\u984c\u306b\u306a\u308b\u306e\u306fG-CSF\u6295\u4e0e\u5f8c\u306e\u9577\u671f\u89b3\u5bdf\u5f8c\u306b\u767d\u8840\u75c5\u304c\u51fa\u3066\u3053\u306a\u3044\u304b\uff1f\u3068\u3044\u3046\u7591\u554f\u3067\u3059\u3002\u3053\u308c\u306f\u4e16\u754c\u7684\u306b\u3082\u30c7\u30fc\u30bf\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u540c\u7a2e\u672b\u68a2\u8840\u5e79\u7d30\u80de\u30c9\u30ca\u30fc\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u4e8b\u696d\u304c\u56fd\u5185\u3067\u8a08\u753b\u3055\u308c\u3066\u4eca\u5e74\u30674\u5e74\u76ee\u3067\u3059\u3002\u3053\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u60c5\u5831\u306f\u3044\u3064\u3082\u65e5\u672c\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d\u5b66\u4f1a\u306eHP\u3067\u898b\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3059\uff08\u6587\u732e\uff11\uff09\u3002\u305d\u308c\u306b\u3088\u308b\u3068\uff0c\u672b\u68a2\u8840\u5e79\u7d30\u80de\u79fb\u690d\u30c9\u30ca\u30fc\u306e\uff12\u4f8b\u306b\u63d0\u4f9b\u304b\u3089\uff11\u5e74\u5f8c\u306b\u8840\u6db2\u60aa\u6027\u75be\u60a3\u304c\u767a\u75c5\u3057\u305f\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308a\u307e\u3057\u305f\u3002\u3057\u304b\u3057\uff0c\u305d\u306e\u56e0\u679c\u95a2\u4fc2\u306f\u5426\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002\u4eca\u5f8c\u3082\uff0c\u3053\u306e\u3088\u3046\u306a\u540c\u7a2e\u672b\u68a2\u8840\u5e79\u7d30\u80de\u30c9\u30ca\u30fc\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u3092\u7d9a\u3051\u3066\u3044\u304f\u3053\u3068\u304cG-CSF\u306e\u6709\u5bb3\u6027\u6709\u7121\u306e\u76e3\u8996\u306b\u306a\u308b\u3068\u601d\u3044\u307e\u3059\u3002\u73fe\u5728\u306e\u7d50\u8ad6\u3068\u3057\u3066\u306fG-CSF\u6295\u4e0e\u3067\u5065\u5eb7\u6210\u4eba\u306b\u76f4\u63a5\u7684\u306b\u767d\u8840\u75c5\u3092\u8a98\u5c0e\u3057\u305f\u3068\u3044\u3046\u4e8b\u5b9f\u306f\u3042\u308a\u307e\u305b\u3093\u3002G-CSF\u6295\u4e0e\u5f8c\u306e\u30c9\u30ca\u30fc\u306b\u9593\u8cea\u6027\u80ba\u708e\u3084\u9759\u8108\u8840\u6813\u75c7\u3092\u5408\u4f75\u3057\u305f\u5831\u544a\u304c\u6700\u8fd1\u3042\u308a\u307e\u3057\u305f\uff08\u6587\u732e\uff11\uff09\u3002\u60c5\u5831\u306e\u96c6\u7a4d\u304c\u5e38\u306b\u5fc5\u8981\u3067\u3059\u3002<\/p>\n

\u767d\u8840\u75c5\u306e\u751f\u5b58\u7387\u304c\u4e0a\u304c\u308b\uff1f<\/p>\n

\u3000\u3067\u306f\uff0c\uff12\uff0e\u306e\u6297\u304c\u3093\u5264\u6295\u4e0e\u5f8c\u306bG-CSF\u3092\u6295\u4e0e\u3059\u308b\u306e\u306f\u5927\u4e08\u592b\u3067\u3057\u3087\u3046\u304b\uff1f\u3082\u3061\u308d\u3093\uff0c\u9aa8\u9ac4\u6027\u767d\u8840\u75c5\u3067\u767d\u8840\u75c5\u7d30\u80de\u304c\u672b\u68a2\u8840\u4e2d\u306b\u898b\u3089\u308c\u308b\u5834\u5408\u306b\u306fG-CSF\u3092\u6295\u4e0e\u3059\u308b\u3053\u3068\u3067\u660e\u3089\u304b\u306b\u767d\u8840\u75c5\u306f\u60aa\u5316\u3057\u307e\u3059\u3002\u305d\u3053\u3067\uff0cG-CSF\u306e\u5b89\u5168\u6027\u3068\u6709\u52b9\u6027\u3092\u8a55\u4fa1\u3059\u308b\u305f\u3081\u306bG-CSF\u6295\u4e0e\u7fa4120\u4f8b\u3068\u975e\u6295\u4e0e\u7fa4125\u4f8b\u306e\u6bd4\u8f03\u8a66\u9a13\u304c\u56fd\u5185\u306e\u591a\u65bd\u8a2d\u3067\u884c\u308f\u308c\u307e\u3057\u305f\u3002\u6025\u6027\u9aa8\u9ac4\u6027\u767d\u8840\u75c5\u306b\u5bfe\u3057\u3066\u5bdb\u89e3\u5c0e\u5165\u7642\u6cd5\u5f8c\u306e\u672b\u68a2\u8840\u4e2d\u304b\u3089\u767d\u8840\u75c5\u7d30\u80de\u304c\u6d88\u3048\u305f\u6642\u671f\u306bG-CSF\u3092\u6295\u4e0e\u3059\u308b\u3068\uff0c\u597d\u4e2d\u7403\u306e\u56de\u5fa9\u3092\u65e9\u3081\uff0812\u65e5\u306818\u65e5\uff09\uff0c\u597d\u4e2d\u7403\u6e1b\u5c11\u6642\u306e\u767a\u71b1\u65e5\u6570\uff08\uff13\u65e5\u3068\uff14\u65e5\uff09\u3092\u5c11\u306a\u304f\u3059\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u3055\u308c\u307e\u3057\u305f\u3002\u751f\u5b58\u7387\u306f\uff12\u7fa4\u9593\u3067\u5dee\u3092\u8a8d\u3081\u307e\u305b\u3093\uff08\u6587\u732e\uff12\uff0c\u56f3\uff11\uff09\u3002\u3057\u305f\u304c\u3063\u3066\uff0cG-CSF\u6295\u4e0e\u306b\u3088\u3063\u3066\u751f\u5b58\u7387\u306f\u4e0d\u5909\u3067\u3059\u304c\u767a\u71b1\u65e5\u6570\u304c\u5c11\u306a\u304f\u597d\u4e2d\u7403\u306e\u56de\u5fa9\u304c\u3088\u3044\u3068\u3044\u3046\u5229\u70b9\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u9020\u8840\u7d30\u80de\u79fb\u690d\u3067\u3082\u540c\u3058\u50be\u5411\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\n\u3000\u3000\u3000 <\/p>\n

G-CSF\u6295\u4e0e\u306bpriming\u52b9\u679c\uff1f
\n\u3000\uff13\uff0e\u306e\u3088\u3046\u306bG-CSF\u3092\u7528\u3044\u3066\u6297\u304c\u3093\u5264\u306e\u52b9\u679c\u3092\u5897\u5f37\u3059\u308b\u8a66\u307f\u304c\u3042\u308a\u307e\u3059\u3002\u767d\u8840\u75c5\u7d30\u80de\u304c\u672b\u68a2\u8840\u4e2d\u306b\u307f\u3089\u308c\u308b\u6642\u671f\u304b\u3089\uff0cG-CSF\u3092\u6297\u304c\u3093\u5264\u3068\u540c\u6642\u306b\u6295\u4e0e\u3057\u305f321\u4f8b\u3068G-CSF\u3092\u4f7f\u7528\u3057\u306a\u3044319\u4f8b\u3068\u306e\u6bd4\u8f03\u6210\u7e3e\u304c\u3042\u308a\u307e\u3059\u3002\u4e2d\u592e\u502455\u30ab\u6708\u306e\u89b3\u5bdf\u306b\u3088\u308b\u751f\u5b58\u7387\u306f42\uff05\u306833\uff05\u3067G-CSF\u4f7f\u7528\u7fa4\u304c\u826f\u304b\u3063\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\u6587\u732e\uff13\uff0c\u56f3\uff12\u306e\uff22\uff09\u3002\u3053\u308c\u306f\u30a2\u30a4\u30c7\u30a2\u3068\u3057\u3066\u306fG-CSF\u306e\u52b9\u679c\u3092\u9006\u306b\u5229\u7528\u3057\u305f\u610f\u5473\u306e\u3042\u308b\u3082\u306e\u3067\u3059\u3002<\/p>\n

\u3000\u3000\u3000 <\/p>\n

\nG-CSF\u6295\u4e0e\u5f8c\u306b\u60aa\u6027\u75be\u60a3\uff1f
\n\u3000\u4e00\u65b9\uff0c\u518d\u751f\u4e0d\u826f\u6027\u8ca7\u8840\u306b\uff11\u5e74\u9593G-CSF\u6295\u4e0e\u5f8c\u306b\u9aa8\u9ac4\u7570\u5f62\u6210\u75c7\u5019\u7fa4\u304c\u767a\u75c7\u3057\u305f\u3068\u306e\u5831\u544a\u304c\u3042\u308a\u307e\u3059\uff08\u6587\u732e\uff14\uff09\u3002\u305d\u306e\u983b\u5ea6\u306f10.4\uff05\u3067\u3059\u3002\u518d\u751f\u4e0d\u826f\u6027\u8ca7\u8840\u3068\u9aa8\u9ac4\u7570\u5f62\u6210\u75c7\u5019\u7fa4\u3068\u306e\u9451\u5225\u304c\u56f0\u96e3\u3067\u3042\u308b\u3053\u3068\u304c\u95a2\u4fc2\u3059\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u518d\u751f\u4e0d\u826f\u6027\u8ca7\u8840\u3067\u306f\u4eca\u5f8c\u3082\u7d4c\u904e\u3092\u89b3\u5bdf\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\u6587\u3000\u3000\u732e
\n\uff11\uff0e\u65e5\u672c\u9020\u8840\u7d30\u80de\u79fb\u690d\u5b66\u4f1a\u30db\u30fc\u30e0\u30da\u30fc\u30b8
\n\u3000\u3000\uff08\uff1ahttp:\/\/www.jshct.com\/\uff09
\n\uff12\uff0eUsuki K et al. Efficacy of granulocyte colony stimulating factor in the treatment of acute myelogeneous leukemia: a multicentre randomized study. Br J Haematol 2002; 116: 103-112.
\n\uff13\uff0eLowenberg B et al. Effect of priming with G-CSF on the outcome of chemotherapy for acute myeloid leukemia. N Engl J Med 2003; 349: 743-752.
\n\uff14\uff0eBessho M et al. Multicenter prospective study of clonal complications in an adult aplastic anemia patients following recombinant human granulocyte colony stimulating factor administration. Int J Hematol. 2003 77: 152-158. <\/p>\n

http:\/\/www.minc.ne.jp\/kasii\/502-3.htm<\/p>\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

G-CSF \u306f\u5b89\u5168\uff1f \u30002000\u5e74\uff14\u6708\u306b\u8a8d\u53ef\u3055\u308c\u305f\u672b\u68a2\u8840\u5e79\u7d30\u80de\u79fb\u690d\u3067\u306fG-CSF\uff08\u9846\u7c92\u7403\u30b3\u30ed\u30cb\u30fc\u523a\u6fc0\u56e0\u5b50\uff09\u3092\u5065\u5eb7\u306a\u30c9\u30ca\u30fc\u306b\u6ce8\u5c04\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u306eG-CSF\u306e\u5b89\u5168\u6027\u306b\u3064\u3044\u3066\u306f\u4ee5\u524d\u3082\u8ff0\u3079\u307e\u3057\u305f\uff08\u9e7f\u5150\u5cf6\u5e02\u533b\u5831\u3000\u7b2c42\u5dfb\u7b2c10\u53f7\uff0c … <\/p>\n

“G-CSF \u306f\u5b89\u5168\uff1f” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-118","post","type-post","status-publish","format-standard","hentry","category-9"],"_links":{"self":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts\/118","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=118"}],"version-history":[{"count":0,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts\/118\/revisions"}],"wp:attachment":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=118"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=118"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=118"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}