{"id":153,"date":"2008-07-20T12:12:15","date_gmt":"2008-07-20T03:12:15","guid":{"rendered":"http:\/\/haruko.km2m.net\/2008\/07\/20\/%e3%83%99%e3%83%b3%e3%83%80%e3%83%a0%e3%82%b9%e3%83%81%e3%83%b3treanda-%e3%81%af%e9%9d%9e%e3%83%9b%e3%82%b8%e3%82%ad%e3%83%b3%e3%83%aa%e3%83%b3%e3%83%91%e8%85%ab%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%ab\/"},"modified":"2008-07-20T12:12:15","modified_gmt":"2008-07-20T03:12:15","slug":"%e3%83%99%e3%83%b3%e3%83%80%e3%83%a0%e3%82%b9%e3%83%81%e3%83%b3treanda-%e3%81%af%e9%9d%9e%e3%83%9b%e3%82%b8%e3%82%ad%e3%83%b3%e3%83%aa%e3%83%b3%e3%83%91%e8%85%ab%e3%81%ae%e6%b2%bb%e7%99%82%e3%81%ab","status":"publish","type":"post","link":"https:\/\/haruko.km2m.net\/?p=153","title":{"rendered":"\u30d9\u30f3\u30c0\u30e0\u30b9\u30c1\u30f3Treanda \u306f\u975e\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\u306e\u6cbb\u7642\u306b\u9855\u8457\u306a\u52b9\u679c"},"content":{"rendered":"

No.191\u3000Bendamustine(\u30d9\u30f3\u30c0\u30e0\u30b9\u30c1\u30f3\uff09TreandaTM\u3000\u30ea\u30f3\u30d1\u816b
\n\u3000\u3000TreandaTM (Bendamustine)\u306f\u975e\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\u306e\u6cbb\u7642\u306b\u9855\u8457\u306a\u52b9\u679c\u304c\u3042\u308b\u65b0\u7642\u6cd5\u3001\u9032\u884c\u671f\u30ea\u30f3\u30d1\u816b\u6cbb\u7642\u306b\u65b0\u305f\u306a\u671f\u5f85\u3092\u3082\u305f\u3089\u3059\/\u30ed\u30c1\u30a7\u30b9\u30bf\u30fc\u5927\u5b66\u533b\u7642\u30bb\u30f3\u30bf\u30fc2005\/12<\/p>\n

2005\u5e7412\u6708\u3001\u30a2\u30e1\u30ea\u30ab\u8840\u6db2\u5b66\u4f1a\uff08ASH\uff09\u7b2c47\u56de\u5e74\u6b21\u7dcf\u4f1a\u3067\u767a\u8868\u3055\u308c\u305f2\u4ef6\u306e\u65b0\u3057\u3044\u7814\u7a76\u304b\u3089\u3001Treanda\u306e\u9759\u8108\u5185\u6295\u4e0e\u304c\u975e\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\uff08NHL\uff09\u306e\u6cbb\u7642\u306b\u304a\u3044\u3066\u9855\u8457\u306a\u52b9\u679c\u304c\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u308b\u3002[1], [2]<\/p>\n

Treanda\u306f\u73fe\u5728\u3044\u308d\u3044\u308d\u306a\u75be\u75c5\u306e\u7b2c2\u76f8\u8a66\u9a13\u306b\u3042\u308b\u30a2\u30eb\u30ad\u30eb\u5316\u6d3b\u6027\u3068\u30d7\u30ea\u30f3\u6d3b\u6027\u3092\u6709\u3059\u308b\u4e8c\u6a5f\u80fd\u6027\u85ac\u5264\u3067\u3042\u308b\u3002Treanda\u306e\u5229\u70b9\u306e\u3072\u3068\u3064\u306f\u4ed6\u306e\u30a2\u30eb\u30ad\u30eb\u5264\u3068\u4ea4\u5dee\u8010\u6027\u304c\u306a\u3044\u3053\u3068\u3067\u3042\u308b\u3002\u30c9\u30a4\u30c4\u3067\u306fNHL\u3001\u6162\u6027\u30ea\u30f3\u30d1\u7403\u767d\u8840\u75c5\u3001\u591a\u767a\u6027\u9aa8\u9ac4\u816b\u3001\u4e73\u764c\u3001\u304a\u3088\u3073\u80ba\u764c\u306a\u3069\u306e\u56fa\u5f62\u816b\u760d\u306e\u6cbb\u7642\u306bTreanda\u304c\u9577\u5e74\u8ca9\u58f2\u3055\u308c\u3001\u81e8\u5e8a\u7684\u306b\u5229\u7528\u3055\u308c\u3066\u304d\u305f\u3002\u30c9\u30a4\u30c4\u3067\u306e\u3042\u308b\u7121\u4f5c\u70ba\u8a66\u9a13\u304b\u3089\u3001BMF\uff08bendamustine\u3001 \u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u30015\u30d5\u30eb\u30aa\u30ed\u30a6\u30e9\u30b7\u30eb\uff09\u306f\u8ee2\u79fb\u6027\u4e73\u764c\u306e\u521d\u56de\u6cbb\u7642\u306b\u304a\u3044\u3066CMF\uff08\u30b7\u30af\u30ed\u30db\u30b9\u30d5\u30a1\u30df\u30c9\u3001\u30e1\u30c8\u30c8\u30ec\u30ad\u30b5\u30fc\u30c8\u30015\u30d5\u30eb\u30aa\u30ed\u30a6\u30e9\u30b7\u30eb\uff09\u3088\u308a\u3082\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002[3]<\/p>\n

\u30c9\u30a4\u30c4\u3067\u5b9f\u65bd\u3055\u308c2005\u5e745\u6708\u306eJournal of Clinical Oncology\u3067\u767a\u8868\u3055\u308c\u305f\u524d\u56de\u306e\u8a66\u9a13\u3067\u306f\u518d\u767a\u6027\u307e\u305f\u306f\u96e3\u6cbb\u6027\u306e\u4f4e\u60aa\u6027\u5ea6NHL\u307e\u305f\u306f\u30de\u30f3\u30c8\u30eb\u7d30\u80de\u30ea\u30f3\u30d1\u816b\u306e\u6cbb\u7642\u306b\u3001Treanda\u304a\u3088\u3073\u30ea\u30c4\u30ad\u30b5\u30f3R\uff08\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\uff09\u304c\u9855\u8457\u306a\u52b9\u679c\u304c\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u308b\u3002 [4]<\/p>\n

\u7c73\u56fd\u304a\u3088\u3073\u30ab\u30ca\u30c0\u306b\u304a\u3051\u308bTreanda\u591a\u65bd\u8a2d\u8a66\u9a13\u3067\u306f\u3001\u5316\u5b66\u7642\u6cd5\u304c\u4e0d\u6210\u529f\u306e\u4f4e\u60aa\u6027\u5ea6\u30ea\u30f3\u30d1\u816b\u307e\u305f\u306f\u30de\u30f3\u30c8\u30eb\u7d30\u80de\u30ea\u30f3\u30d1\u816b\u306e\u60a3\u800567\u4f8b\u3067Treanda\u304c\u30ea\u30c4\u30ad\u30b5\u30f3\u3068\u4f75\u7528\u3057\u3066\u8a55\u4fa1\u3055\u308c\u3001ASH2005\u3067\u767a\u8868\u3055\u308c\u305f\u300237\u30d1\u30fc\u30bb\u30f3\u30c8\u3067\u306f\u30ea\u30c4\u30ad\u30b5\u30f3\u306b\u3088\u308b\u6cbb\u7642\u3082\u4e0d\u6210\u529f\u306b\u7d42\u308f\u3063\u3066\u3044\u305f\u3002<\/p>\n

\u5168\u594f\u52b9\u7387\u306f87\u30d1\u30fc\u30bb\u30f3\u30c8\u3067\u300133\u30d1\u30fc\u30bb\u30f3\u30c8\u306e\u5b8c\u5168\u5bdb\u89e3\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002\u6700\u3082\u591a\u304f\u898b\u3089\u308c\u305f\u5408\u4f75\u75c7\u306f\u53ef\u9006\u6027\u9aa8\u9ac4\u6bd2\u6027\u306b\u95a2\u3059\u308b\u3082\u306e\u3067\u3042\u3063\u305f\u3002<\/p>\n

\u30c9\u30a4\u30c4\u306e\u7814\u7a76\u8005\u306f\u307e\u305f\u3001\u4f4e\u60aa\u6027\u5ea6NHL\u307e\u305f\u306f\u30de\u30f3\u30c8\u30eb\u7d30\u80de\u30ea\u30f3\u30d1\u816b\u306e\u60a3\u8005164\u4f8b\u306b\u5bfe\u3057BOP\uff08bendamustine\u3001\u30aa\u30f3\u30b3\u30d3\u30f3\u3001\u30d7\u30ec\u30c9\u30cb\u30be\u30f3\uff09\u3068COP\uff08\u30b7\u30af\u30ed\u30db\u30b9\u30d5\u30a1\u30df\u30c9\u3001\u30aa\u30f3\u30b3\u30d3\u30f3\u3001\u30d7\u30ec\u30c9\u30cb\u30be\u30f3\uff09\u3092\u6bd4\u8f03\u3059\u308b\u7121\u4f5c\u70ba\u8a66\u9a13\u3092\u3082\u5b9f\u65bd\u3057\u305f\u3002[5] \u5b8c\u5168\u5bdb\u89e3\u7387\u306f\u4f3c\u901a\u3063\u3066\u3044\u305f\u304c\u30015\u5e74\u751f\u5b58\u7387\u306fCOP\uff0846%\uff09\u3068\u6bd4\u8f03\u3057BOP\uff0861%\uff09\u306e\u65b9\u304c\u9ad8\u304b\u3063\u305f\u3002\u6bd2\u6027\u306f\u3044\u305a\u308c\u306e\u6cbb\u7642\u65b9\u6cd5\u3067\u3082\u8a31\u5bb9\u7bc4\u56f2\u5185\u3067\u3042\u3063\u305f\u3002<\/p>\n

ASH2005\u3067\u767a\u8868\u3055\u308c\u305f\u7b2c\u4e8c\u306e\u8a66\u9a13\u3082\u7c73\u56fd\u304a\u3088\u3073\u30ab\u30ca\u30c0\u306e17\u306e\u65bd\u8a2d\u3067\u518d\u767a\u6027\u307e\u305f\u306f\u96e3\u6cbb\u6027NHL\u306e\u60a3\u800577\u4f8b\u3092\u5bfe\u8c61\u306b\u5b9f\u65bd\u3055\u308c\u305f\u3002\u7d04\u534a\u6570\u306e\u60a3\u8005\u306b\u6ffe\u80de\u6027NHL\u304c\u898b\u3089\u308c\u3001\u6b8b\u308a\u306e\u60a3\u8005\u306b\u306f\u60aa\u6027\u5ea6\u304c\u3088\u308a\u9ad8\u3044\u7d44\u7e54\u50cf\u304c\u898b\u3089\u308c\u305f\u3002\u5168\u54e1\u304cTreanda\u5358\u5264\u3067\u6cbb\u7642\u3092\u53d7\u3051\u305f\u7d50\u679c\u3001\u5168\u594f\u52b9\u7387\u306f74%\u3001\u5b8c\u5168\u5bdb\u89e3\u7387\u306f39%\u3067\u3042\u3063\u305f\u3002\u594f\u52b9\u671f\u9593\u4e2d\u592e\u5024\u306f6.6\u30b1\u6708\u3067\u7d44\u7e54\u5b66\u7684\u8ee2\u63db\u306e\u60a3\u8005\u3088\u308a\u3082\u6ffe\u80de\u6027\u30ea\u30f3\u30d1\u816b\u306e\u60a3\u8005\u306e\u65b9\u304c\u9577\u304b\u3063\u305f\u3002\u526f\u4f5c\u7528\u306f\u4e3b\u306b\u9aa8\u9ac4\u6291\u5236\u306b\u95a2\u9023\u3057\u305f\u3082\u306e\u3067\u3042\u3063\u305f\u3002<\/p>\n

\u30b3\u30e1\u30f3\u30c8\uff1a\u3053\u308c\u3089\u306e\u8a66\u9a13\u3088\u308a\u3001NHL\u304a\u3088\u3073\u4ed6\u306e\u764c\u306e\u6cbb\u7642\u306b\u7528\u3044\u308b\u7b2c\u4e00\u306e\u30a2\u30eb\u30ad\u30eb\u5316\u85ac\u3068\u3057\u3066Treanda\u304c\u30b7\u30af\u30ed\u30db\u30b9\u30d5\u30a1\u30df\u30c9\u306b\u53d6\u3063\u3066\u4ee3\u308f\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u308b\u3002<\/p>\n

\uff08Chihiro\u3000\u8a33\u30fbDr.Saru\u3000\u76e3\u4fee\uff09<\/p>\n

http:\/\/www.cancerit.jp\/archive191bendamustin.html<\/p>\n","protected":false},"excerpt":{"rendered":"

No.191\u3000Bendamustine(\u30d9\u30f3\u30c0\u30e0\u30b9\u30c1\u30f3\uff09TreandaTM\u3000\u30ea\u30f3\u30d1\u816b \u3000\u3000TreandaTM (Bendamustine)\u306f\u975e\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\u306e\u6cbb\u7642\u306b\u9855\u8457\u306a\u52b9\u679c\u304c\u3042\u308b\u65b0\u7642\u6cd5\u3001\u9032\u884c\u671f\u30ea\u30f3\u30d1\u816b\u6cbb\u7642\u306b\u65b0\u305f\u306a\u671f\u5f85 … <\/p>\n

“\u30d9\u30f3\u30c0\u30e0\u30b9\u30c1\u30f3Treanda \u306f\u975e\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\u306e\u6cbb\u7642\u306b\u9855\u8457\u306a\u52b9\u679c” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-153","post","type-post","status-publish","format-standard","hentry","category-4"],"_links":{"self":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts\/153","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=153"}],"version-history":[{"count":0,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts\/153\/revisions"}],"wp:attachment":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=153"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=153"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=153"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}