{"id":25,"date":"2004-01-01T21:18:30","date_gmt":"2004-01-01T12:18:30","guid":{"rendered":"http:\/\/haruko.km2m.net\/2004\/01\/01\/bexxar\/"},"modified":"2004-01-01T21:18:30","modified_gmt":"2004-01-01T12:18:30","slug":"bexxar","status":"publish","type":"post","link":"https:\/\/haruko.km2m.net\/?p=25","title":{"rendered":"Bexxar"},"content":{"rendered":"

Bexxar\u4e8c\u91cd\u4f5c\u7528\u653e\u5c04\u6027\u6297\u4f53\u85ac\/\u30df\u30b7\u30ac\u30f3\u5927\u5b66<\/p>\n

\u30df\u30b7\u30ac\u30f3\u5927\u3001FDA\u627f\u8a8d(2003\/6)\u4ee5\u6765\u521d\u306e\u30ea\u30f3\u30d1\u816bBexxar\u7642\u6cd5\u30ec\u30b8\u30e1\u30f3\u6cbb\u7642\u3092\u5b9f\u65bd2004\/1<\/p>\n

January 1, 2004
\nFirst lymphoma patients treated with BexxarR therapeutic regimen at UMHS since FDA approval<\/p>\n

Mark Kaminski, M.D\u6c0f\u3068\u305d\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u300110\u5e74\u4ee5\u4e0a\u524d\u306b\u3053\u306e\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u3092\u59cb\u3081\u3066\u3044\u305f\u3002\u4eca\u56de\u3001Kaminski\u306f\u3001FDA\u627f\u8a8d\uff082003\/6\uff09\u4ee5\u6765\u521d\u3081\u3066\u306e\u60a3\u8005\u306bBexxar\u6cbb\u7642\u3092\u65bd\u3057\u305f\u3002<\/p>\n

\u300cBexxar\u306f\u6cbb\u7642\u306e\u9769\u65b0\u3067\u3042\u308b\u3002\u3068\u3001Kaminski\u6c0f\uff08co-director of the Leukemia\/Lymphoma\/Bone Marrow Transplant Program at the U-M Comprehensive Cancer Center\uff0d\u30df\u30b7\u30ac\u30f3\u5927\u7dcf\u5408\u304c\u3093\u30bb\u30f3\u30bf\u30fc\u306e\u2018\u767d\u8840\u75c5\u3001\u30ea\u30f3\u30d1\u816b\u3001\u9aa8\u9ac4\u79fb\u690d\u30d7\u30ed\u30b0\u30e9\u30e0\u2019\u5171\u540c\u30c7\u30a3\u30ec\u30af\u30bf\u30fc\uff09\u306f\u8a00\u3046\u3002Bexxar\u4ee5\u524d\u306f\u3001\u307b\u3068\u3093\u3069\u306e\u6cbb\u7642\u306f\u3001\u5316\u5b66\u7642\u6cd5\u3068\u5916\u90e8\u7167\u5c04\u7642\u6cd5\u306b\u983c\u3063\u3066\u3044\u305f\u304c\u3001\u305d\u308c\u3089\u306f\u5fc5\u305a\u3057\u3082\u52b9\u679c\u3092\u5f97\u3089\u308c\u305a\u3001\u60a3\u8005\u306b\u3068\u3063\u3066\u6bd2\u6027\u306e\u3042\u308b\u6cbb\u7642\u3042\u3063\u305f\u3002\u3053\u308c\u307e\u3067\u306e\u5316\u5b66\u7642\u6cd5\u3068\u653e\u5c04\u7dda\u7642\u6cd5\u304c\u764c\u7d30\u80de\u3060\u3051\u3067\u306a\u304f\u3001\u6b63\u5e38\u7d30\u80de\u3082\u6bba\u50b7\u3059\u308b\u306e\u306b\u5bfe\u3057\u3001Bexxar\u7642\u6cd5\u306e\u30ec\u30b8\u30e1\u30f3\u306f\u3001\u764c\u7d30\u80de\u3060\u3051\u3092\u6a19\u7684\u3068\u3059\u308b\u653e\u5c04\u7269\u3092\u4f7f\u7528\u3059\u308b\u3002\u60a3\u8005\u306f\u3001\u4f55\u30af\u30fc\u30eb\u3001\u4f55\u30f6\u6708\u3082\u306e\u5316\u5b66\u7642\u6cd5\u306e\u4ee3\u308f\u308a\u306b\u3001\u305f\u3063\u305f1\u672c\u306e\u6ce8\u5c04\u3092\u6253\u3064\u3060\u3051\u3067\u3042\u308b\u3002\u305d\u3057\u3066\u526f\u4f5c\u7528\u3082\u304d\u308f\u3081\u3066\u5c11\u306a\u3044\u3002<\/p>\n

Kaminski\u6c0f\u306f\u3001\u81e8\u5e8a\u8a66\u9a13\u3067Bexxar\u3092\u4f7f\u7528\u3057\u3066\u304d\u305f\u304c\u30016\u6708\uff082003\u5e74\uff09\u306bFDA\u306f\u3001\u4ed6\u306e\u6cbb\u7642\u306b\u62b5\u6297\u6027\u3068\u306a\u3063\u305f\u30ce\u30f3\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\uff08NHL\uff09\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u3068\u3057\u3066\u8a8d\u53ef\u3057\u305f\u3002\u30e1\u30c7\u30a3\u30b1\u30a2\uff08\u9ad8\u9f62\u8005\u5411\u3051\u533b\u7642\u4fdd\u967a\u5236\u5ea6\uff09\u306f\u3001Bexxar\u6cbb\u7642\u306b\u4fdd\u967a\u3092\u9069\u7528\u3059\u308b\u3068\u767a\u8868\u3057\u305f\u3002\uff08\u7565\uff09<\/p>\n

Bexxar\u306f\u3001\u5316\u5b66\u7642\u6cd5\u3092\u53d7\u3051\u305f\u6ffe\u80de\u6027\u30ea\u30f3\u30d1\u816b\u3078\u306e\u4f7f\u7528\u306b\u8a8d\u53ef\u3055\u308c\u305f\u3002Bexxar \u306f\u3001\u816b\u760d\u6a19\u7684\u3068\u3059\u308b\u6297\u60aa\u6027\u65b0\u751f\u7269\uff08\u6297\u764c\uff09\u30e2\u30ce\u30af\u30ed\u30ca\u30fc\u30eb\u6297\u4f53(Tositumomab)\u3068\u3001\u500b\u5225\u306b\u653e\u5c04\u7dda\u91cf\u3092\u8a2d\u5b9a\u3059\u308b\u6cbb\u7642\u6cd5\u3092\u3042\u308f\u305b\u3082\u3063\u305f\u4e8c\u91cd\u4f5c\u7528\u306e\u6cbb\u7642\u6cd5\u3067\u3042\u308b\u3002\u7d44\u307f\u5408\u308f\u3055\u308c\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u3053\u308c\u3089\u306e\u7269\u8cea\u306f\u3001\u653e\u5c04\u6027\u6a19\u8b58\u5316\u30e2\u30ce\u30af\u30ed\u30ca\u30fc\u30eb\u6297\u4f53\u3068\u306a\u308a\u3001\u4f53\u4e2d\u3092\u5de1\u3063\u3066\u764c\u7d30\u80de\u4e0a\u306b\u767a\u898b\u3055\u308c\u305f\u6a19\u7684\u3068\u3059\u308b\u6297\u539f\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u764c\u7d30\u80de\u306b\u5bfe\u3057\u3066\u514d\u75ab\u53cd\u5fdc\u3092\u8a98\u5f15\u3057\u3001\u307e\u305f\u653e\u5c04\u6027\u7269\u8cea\u3092\u76f4\u63a5\u816b\u760d\u3078\u904b\u3076\u3053\u3068\u306b\u306a\u308b\u3002Bexxar\u306f\u3001\u500b\u5225\u306b\u6307\u5b9a\u3055\u308c\u305f\u30af\u30ea\u30a2\u30e9\u30f3\u30b9\u5024\u306b\u57fa\u3044\u3066\u6295\u4e0e\u3067\u304d\u308b\u552f\u4e00\u306eNHL\u6cbb\u7642\u3067\u3042\u308a\u3001\u305d\u308c\u305e\u308c\u306e\u60a3\u8005\u306b\u5fdc\u3058\u3066\u524d\u3082\u3063\u3066\u6c7a\u3081\u3089\u308c\u305f\u7dda\u91cf\u306e\u653e\u5c04\u6027\u7269\u8cea\u3092\u904b\u3076\u3053\u3068\u304c\u53ef\u80fd\u3068\u306a\u3063\u305f\u3002<\/p>\n

\u300c\u5b9f\u969b\u3001B-Cell\u3068\u547c\u3070\u308c\u308b\u30ea\u30f3\u30d1\u7403\u304b\u3089\u767a\u751f\u3059\u308b\u3059\u3079\u3066\u306e\u30ea\u30f3\u30d1\u816b\u306f\u3001\u7d30\u80de\u8868\u9762\u306bCD20\u3068\u3044\u3046\u86cb\u767d\u8cea\u3092\u6301\u3064\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002\u300d\u3068\u3001\u30df\u30b7\u30ac\u30f3\u5927\u5b66\u6838\u533b\u5b66\u30d1\u30a4\u30aa\u30cb\u30a2\u3067\u3042\u308bRichard Wahl, M.D.\u6c0f \uff08\u73fe\u5728Johns Hopkins University Medical Center\u6838\u533b\u5b66\u6559\u6388\uff09\u3068\u3068\u3082\u306b\u6cbb\u7642\u3092\u958b\u767a\u3057\u3066\u304d\u305fKaminski\u6c0f\u306f\u8ff0\u3079\u305f\u3002<\/p>\n

\u300c\u6211\u3005\u304c\u30e9\u30b8\u30aa\u30a2\u30a4\u30bd\u30c8\u30fc\u30d7\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u6297\u4f53\u306f\u3001\u3053\u306eCD20\u3068\u3044\u3046\u30bf\u30fc\u30b2\u30c3\u30c8\u306b\u7d5e\u3063\u3066\u8a8d\u8b58\u3057\u3001\u3057\u3063\u304b\u308a\u3068\u4ed8\u7740\u3059\u308b\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u3053\u306e\u6297\u4f53\u3092\u8840\u6d41\u306b\u5c0e\u5165\u3059\u308b\u3068\u3001\u305d\u308c\u306f\u3001\u3053\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\u3092\u6301\u3064\u7d30\u80de\u3084\u3082\u306e\u306b\u81ea\u7136\u3068\u7d50\u5408\u3059\u308b\u3002\u300d<\/p>\n

\u4e00\u65e6\u3001\u305d\u308c\u304cCD20\u306b\u7d50\u5408\u3059\u308b\u3068\u3001\u30e9\u30b8\u30aa\u30a2\u30a4\u30bd\u30c8\u30fc\u30d7\u304c\u5f37\u529b\u306a\u7c92\u5b50\u3092\u653e\u51fa\u3001\u816b\u760d\u7d30\u80de\u306b\u7a81\u6483\u3057\u3001\u305d\u306e\u5468\u8fba\u306e\u764c\u7d30\u80de\u3060\u3051\u3092\u6bba\u50b7\u3059\u308b\u3002<\/p>\n

Bexxar\u6cbb\u7642\u306f\u3001\u60a3\u8005\u3092\u5614\u6c17\u3084\u8131\u6bdb\u3068\u3044\u3063\u305f\u526f\u4f5c\u7528\u304b\u3089\u89e3\u653e\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u5316\u5b66\u7642\u6cd5\u3088\u308a\u901f\u3044\u3002\u5316\u5b66\u7642\u6cd5\u304c\u30013\uff5e4\u9031\u9593\u30b5\u30a4\u30af\u30eb\u30676\uff5e8\u30f6\u6708\u304b\u304b\u308b\u306e\u306b\u5bfe\u3057\u3001Bexxar\u306f1\u9031\u9593\u4ee5\u5185\u3067\u7d42\u4e86\u3059\u308b\u3002<\/p>\n

\u6cbb\u7642\u306e\u521d\u65e5\u306b\u60a3\u8005\u306fBexxar\u306e\u30c6\u30b9\u30c8\u6295\u4e0e\u306e\u305f\u3081\u306e\u6ce8\u5c04\u3092\u6253\u3064\u3002\u305d\u308c\u306b\u3088\u3063\u3066\u3001\u60a3\u8005\u306e\u4f53\u304c\u6a19\u8b58Bexxar\u3092\u3069\u306e\u3088\u3046\u306b\u51e6\u7406\u3059\u308b\u304b\u3092\u307f\u308b\u3002\u6838\u533b\u5b66\u30b9\u30ad\u30e3\u30f3\u3067Bexxar\u304c\u3069\u306e\u304f\u3089\u3044\u306e\u901f\u5ea6\u3067\u816b\u760d\u306b\u9054\u3057\u3001\u307e\u305f\u653e\u5c04\u6027\u7269\u8cea\u304c\u3069\u306e\u304f\u3089\u3044\u3067\u60a3\u8005\u306e\u4f53\u304b\u3089\u6d88\u5931\u3059\u308b\u304b\u3092\u5224\u5b9a\u3059\u308b\u3002\u305d\u306e\u6642\u70b9\u3067\u3001\u816b\u760d\u533b\u306f\u305d\u306e\u60a3\u8005\u306b\u5fdc\u3058\u305fBexxar\u306e\u6295\u4e0e\u91cf\u3092\u304d\u3081\u308b\u3002\u60a3\u8005\u306f\u3001\u30c6\u30b9\u30c8\u6ce8\u5c04\u304b\u30891\u9031\u9593\u3067\u6cbb\u7642\u3092\u59cb\u3081\u308b\u3002\u60a3\u8005\u306f\u5408\u8a08\u30674\u56de\u306e\u901a\u9662\u3067\u3059\u3080\uff0d1\u56de\u76ee\u30c6\u30b9\u30c8\u6295\u4e0e\u30012\u30013\u56de\u76ee\u6838\u533b\u5b66\u30b9\u30ad\u30e3\u30f3\u30014\u56de\u76ee\u6cbb\u7642\u6295\u4e0e\u3067\u3042\u308b\u3002<\/p>\n

\u300c\u6cbb\u7642\u306f\u305d\u308c\u3067\u7d42\u308f\u308a\u3067\u3059\u3002\u518d\u5ea6\u306e\u30b5\u30a4\u30af\u30eb\u306a\u3069\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u60a3\u8005\u306f\u5e30\u5b85\u3057\u3001\u6cbb\u7642\u306f\u6295\u4e0e\u3055\u308c\u305f\u77ac\u9593\u304b\u3089\u52b9\u679c\u3092\u8868\u3057\u59cb\u3081\u308b\u306e\u3067\u3059\u3002\u300d\u3068Kaminski\u6c0f\u306f\u8a00\u3046\u3002<\/p>\n

6\uff5e8\u9031\u9593\u3067CT\u30b9\u30ad\u30e3\u30f3\u3001\u8eab\u4f53\u3001\u8840\u6db2\u306e\u691c\u67fb\u3092\u3046\u3051\u3066\u6cbb\u7642\u306e\u52b9\u679c\u304c\u3042\u3063\u305f\u304b\u3069\u3046\u304b\u307f\u307e\u3059\u3002\u533b\u5e2b\u306f\u3053\u306e\u3068\u304d\u3001\u305d\u306e\u30ea\u30f3\u30d1\u816b\u304c\u5bdb\u89e3\u306b\u81f3\u3063\u305f\u304b\u3069\u3046\u304b\u5224\u5b9a\u3067\u304d\u308b\u306e\u3067\u3059\u3002<\/p>\n

Bexxar\u6cbb\u7642\u3092\u53d7\u3051\u308b\u60a3\u8005\u306e\u591a\u304f\u304c\u3001\u3059\u3067\u306b\u4f55\u30b5\u30a4\u30af\u30eb\u3082\u306e\u5316\u5b66\u7642\u6cd5\u3092\u53d7\u3051\u3066\u304a\u308a\u3001\u901a\u5e38\u306e\u6297\u764c\u5264\u306b\u53cd\u5fdc\u3057\u306a\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u6614\u304b\u3089\u3001NHL\u306e\u4e88\u5f8c\u306f\u3088\u304f\u3042\u308a\u307e\u305b\u3093\u304c\u3001\u3053\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u300170%\u306e\u60a3\u8005\u304cBexxar\u306b\u53cd\u5fdc\u3057\u300120\uff5e30\uff05\u306e\u60a3\u8005\u304c\u5b8c\u5168\u5bdb\u89e3\uff0d\u753b\u50cf\u8a3a\u65ad\u3067\u3082\u751f\u691c\u3067\u3082\u4e00\u5207\u30ea\u30f3\u30d1\u816b\u304c\u8a8d\u3081\u3089\u308c\u306a\u3044\u72b6\u614b\u306b\u81f3\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u3053\u306e\u6cbb\u7642\u306e\u6709\u671b\u306a\u3068\u3053\u308d\u306f\u3001\u304b\u3064\u3066\u306a\u3044\u307b\u3069\u591a\u304f\u306e\u60a3\u8005\u304c\u3001\u526f\u4f5c\u7528\u3082\u306a\u304f\u75c5\u6c17\u306a\u3057\u306b\u66ae\u3089\u305b\u308b\u3053\u3068\u3067\u3059\u3002\u3053\u306e\u3053\u3068\u306f\u3001\u3082\u306f\u3084\u9078\u629e\u80a2\u306e\u306a\u304f\u306a\u3063\u305f\u60a3\u8005\u306b\u3001\u3042\u3089\u305f\u306a\u30aa\u30d7\u30b7\u30e7\u30f3\u3068\u5e0c\u671b\u3092\u63d0\u4f9b\u3059\u308b\u3067\u3057\u3087\u3046\u3002\u300d\u3068\u3001Kasinski\u6c0f\u306f\u8a9e\u3063\u305f\u3002<\/p>\n

http:\/\/www.med.umich.edu\/opm\/newspage\/2004\/bexxar.htm<\/p>\n

\n\u88fd\u54c1\u60c5\u5831
\nBexxarR\u3000\/\u3000Corixa Corp., GlaxoSmithKline
\nHP: www.bexxar.com \u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000
\n\u3000\u3000\u3000\u3000\u3000
\n\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000\u3000
\n\u91ce\u4e2d\u3000\u5e0c\u3000\u8a33<\/p>\n

\nhttp:\/\/www.cancerit.jp\/archive37Bexxar.html#1nshkb<\/p>\n","protected":false},"excerpt":{"rendered":"

Bexxar\u4e8c\u91cd\u4f5c\u7528\u653e\u5c04\u6027\u6297\u4f53\u85ac\/\u30df\u30b7\u30ac\u30f3\u5927\u5b66 \u30df\u30b7\u30ac\u30f3\u5927\u3001FDA\u627f\u8a8d(2003\/6)\u4ee5\u6765\u521d\u306e\u30ea\u30f3\u30d1\u816bBexxar\u7642\u6cd5\u30ec\u30b8\u30e1\u30f3\u6cbb\u7642\u3092\u5b9f\u65bd2004\/1 January 1, 2004 First lymphoma pati … <\/p>\n

“Bexxar” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-25","post","type-post","status-publish","format-standard","hentry","category-4"],"_links":{"self":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts\/25","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=25"}],"version-history":[{"count":0,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts\/25\/revisions"}],"wp:attachment":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=25"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=25"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=25"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}