\u96e3\u6cbb\u6027\u306e\u518d\u767a\u6027\u4f4e\u60aa\u6027\u5ea6B\u7d30\u80de\u975e\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\u306b\u5bfe\u3059\u308bInotuzumab Ozogamicin\u306e\u6709\u52b9\u6027\u3092\u30d5\u30a7\u30fc\u30ba2\u3067\u78ba\u8a8d\u3010\u8840\u6db2\u5b66\u4f1a2011\u3011 \u68ee\u4e0b\u7d00\u4ee3\u7f8e\uff1d\u533b\u5b66\u30e9\u30a4\u30bf\u30fc 2011. 10. 20<\/p>\n
\u5b66\u4f1a\u30b9\u30da\u30b7\u30e3\u30eb\uff1a\u7b2c73\u56de\u65e5\u672c\u8840\u6db2\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a 2011\u5e7410\u670814\u65e5\uff5e16\u65e5\u3000\u540d\u53e4\u5c4b<\/p>\n
\n\u8a73\u3057\u304f\u306f\u3001\u65e5\u7d4c\u30e1\u30c7\u30a3\u30ab\u30eb
\nhttp:\/\/medical.nikkeibp.co.jp\/leaf\/all\/gakkai\/sp\/jshjsch2011\/201110\/522056.html<\/p>\n
\n\u3000\u6297CD22\u6297\u4f53\u3092\u30ab\u30ea\u30b1\u30a2\u30df\u30b7\u30f3\u306b\u7d50\u5408\u3055\u305b\u305f\u88fd\u5264\u3001Inotuzumab Ozogamicin\u306f\u3001\u96e3\u6cbb\u6027\u306e\u518d\u767a\u6027\u4f4e\u60aa\u6027\u5ea6B\u7d30\u80de\u975e\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\uff08B-NHL\uff09\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u81e8\u5e8a\u7684\u306a\u6709\u52b9\u6027\u304c\u660e\u3089\u304b\u3067\u6bd2\u6027\u3082\u7ba1\u7406\u53ef\u80fd\u3067\u3042\u308b\u3053\u3068\u304c\u3001\u56fd\u969b\u7684\u306a\u591a\u65bd\u8a2d\u5171\u540c\u306e\u30d5\u30a7\u30fc\u30ba2\u8a66\u9a13\u304b\u3089\u793a\u3055\u308c\u305f\u300210\u670814\u65e5\u304b\u308916\u65e5\u307e\u3067\u540d\u53e4\u5c4b\u5e02\u3067\u958b\u50ac\u3055\u308c\u305f\u7b2c73\u56de\u65e5\u672c\u8840\u6db2\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u3067\u3001\u540d\u53e4\u5c4b\u7b2c\u4e8c\u8d64\u5341\u5b57\u75c5\u9662\u8840\u6db2\u30fb\u816b\u760d\u5185\u79d1\u306e\u5c0f\u690b\u7f8e\u77e5\u5247\u6c0f\u304c\u767a\u8868\u3057\u305f\u3002<\/p>\n
\u3000Inotuzumab Ozogamicin\u306f\u3001\u7c73\u56fd\u3068\u65e5\u672c\u3067\u884c\u308f\u308c\u305f\u30d5\u30a7\u30fc\u30ba1\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001\u518d\u767a\/\u96e3\u6cbb\u6027\u306eB-NHL\u60a3\u8005\u306b\u5bfe\u3059\u308b\u6709\u52b9\u6027\u3068\u5b89\u5168\u6027\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\u3002
\n\u3000
\n\u3000\u4eca\u56de\u3001\u5c0f\u690b\u6c0f\u3089\u306f\u3001\u5358\u7fa4\u3001\u975e\u76f2\u691c\u3001\u30d5\u30a7\u30fc\u30ba2\u306e\u56fd\u969b\u5171\u540c\u8a66\u9a13\u3092\u884c\u3044\u3001\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3001\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3068\u5316\u5b66\u7642\u6cd5\u306e\u4f75\u7528\u3001\u653e\u5c04\u514d\u75ab\u7642\u6cd5\uff08RIT\uff09\u306b\u96e3\u6cbb\u6027\u3067CD22\u967d\u6027\u306e\u518d\u767a\u6027\u4f4e\u60aa\u6027\u5ea6B-NHL\u306e\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u3001Inotuzumab Ozogamicin\u306e\u5b89\u5168\u6027\u3068\u6709\u52b9\u6027\u3092\u8a55\u4fa1\u3057\u305f\u3002<\/p>\n
\u3000\u5bfe\u8c61\u306f\u30012\u56de\u4ee5\u4e0a\u306e\u5168\u8eab\u7642\u6cd5\u3092\u65bd\u884c\u5f8c\u306b\u9032\u884c\u3092\u8a8d\u3081\u3001\u6700\u5f8c\u306b\u884c\u3063\u305f\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3092\u542b\u3080\u6cbb\u7642\u306e\u7d42\u4e86\u304b\u30896\u30ab\u6708\u4ee5\u5185\u3001\u307e\u305f\u306f\u6297CD20\u6297\u4f53\u306b\u3088\u308bRIT\u306e\u7d42\u4e86\u304b\u308912\u30ab\u6708\u4ee5\u5185\u306b\u5bdb\u89e3\u304c\u307f\u3089\u308c\u306a\u3044\u3001\u307e\u305f\u306f\u9032\u884c\u3092\u8a8d\u3081\u305f\u60a3\u8005\u3068\u3057\u305f\u3002<\/p>\n
\u3000Inotuzumab Ozogamicin\u306f1.8mg\/m2\u3092\u70b9\u6ef4\u9759\u6ce8\u306728\u65e5\u3054\u3068\u306b\u6295\u4e0e\u3057\u30014\u30b5\u30a4\u30af\u30eb\u884c\u3046\u3053\u3068\u3068\u3057\u305f\u3002\u7528\u91cf\u3084\u983b\u5ea6\u306f\u6bd2\u6027\u306b\u57fa\u3065\u3044\u3066\u8abf\u6574\u3057\u305f\u3002\u5b8c\u5168\u5bdb\u89e3\uff08CR\uff09\u3092\u5f97\u305f\u5f8c\u306f2\u30b5\u30a4\u30af\u30eb\u307e\u3067\u8ffd\u52a0\u6295\u4e0e\u3092\u8a8d\u3081\u3001\u6295\u4e0e\u306f\u6700\u9577\u30678\u30b5\u30a4\u30af\u30eb\u307e\u3067\u3068\u3057\u305f\u3002\u521d\u56de\u6295\u4e0e\u304b\u3089\u6700\u95772\u5e74\u307e\u3067\u8ffd\u8de1\u3057\u305f\u3002<\/p>\n
\u300081\u4eba\u304c\u767b\u9332\u3055\u308c\u3001\u5185\u8a33\u306f\u3001\u6ffe\u80de\u6027\u30ea\u30f3\u30d1\u816b\uff08FL\uff0972\u4eba\uff08\u5e74\u9f62\u4e2d\u592e\u502462.0\u6b73\u3001\u7537\u602751\uff05\uff09\u3001\u8fba\u7e01\u5c64\u30ea\u30f3\u30d1\u816b4\u4eba\uff08\u540c70.5\u6b73\u300150\uff05\uff09\u3001\u5c0f\u30ea\u30f3\u30d1\u7403\u6027\u30ea\u30f3\u30d1\u816b\uff08SLL\uff095\u4eba\uff0867.0\u6b73\u3001100\uff05\uff09\u3060\u3063\u305f\u3002\u524d\u6cbb\u7642\u306e\u3046\u3061\u3001\u6700\u5f8c\u306e\u6cbb\u7642\u304c\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u3060\u3063\u305f\u306e\u306f\u3001FL\u7fa471\uff05\u3001\u8fba\u7e01\u5c64\u30ea\u30f3\u30d1\u816b\u7fa450\uff05\u3001SLL\u7fa480\uff05\u3060\u3063\u305f\u3002FL\u7fa4\u3067\u306f7\uff05\u304c\u5e79\u7d30\u80de\u79fb\u690d\u3092\u53d7\u3051\u3066\u3044\u305f\u3002<\/p>\n
\u3000FL\u7fa4\u3067\u8a66\u9a13\u6cbb\u7642\u3092\u5b8c\u4e86\u3057\u305f\u306e\u306f15\uff05\u3001\u65e9\u671f\u306e\u6cbb\u7642\u4e2d\u6b62\u306f67\uff05\u3067\u300140\uff05\u306f\u6709\u5bb3\u4e8b\u8c61\u306b\u3088\u308b\u3082\u306e\u3060\u3063\u305f\u3002\u5bfe\u8c61\u5168\u4f53\u3067\u306f\u3001\u6295\u4e0e\u306e\u4e2d\u592e\u5024\u306f3\u56de\uff08\u7bc4\u56f2\uff1a1\uff5e8\uff09\u3060\u3063\u305f\u3002<\/p>\n
\u3000\u60a3\u8005\u306e20\uff05\u4ee5\u4e0a\u3067\u5831\u544a\u3055\u308c\u305f\u6cbb\u7642\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\uff08TEAE\uff09\u3067\u306f\u3001\u8840\u5c0f\u677f\u6e1b\u5c11\u3068\u597d\u4e2d\u7403\u6e1b\u5c11\u304c\u591a\u304f\u3001\u30b0\u30ec\u30fc\u30c93\u4ee5\u4e0a\u306f\u305d\u308c\u305e\u308c57\uff05\u306826\uff05\u3060\u3063\u305f\u3002\u30b0\u30ec\u30fc\u30c93\u4ee5\u4e0a\u306e\u975e\u8840\u6db2\u6bd2\u6027\u306f\u3001\u5614\u6c17\u304c5\uff05\u3001AST\u4e0a\u6607\u304c4\uff05\u3001\u98df\u6b32\u4e0d\u632f\u3084\u75b2\u52b4\u611f\u306a\u3069\u304c\u54043\uff05\u306b\u767a\u73fe\u3057\u305f\u300218\u4eba\u306e\u60a3\u8005\u306b\u3064\u3044\u3066\u300146\u4ef6\u306e\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u304c\u5831\u544a\u3055\u308c\u305f\u304c\u3001\u3053\u306e\u3046\u3061Inotuzumab Ozogamicin\u306b\u95a2\u9023\u3059\u308b\u4e8b\u8c61\u306f43\uff05\u3060\u3063\u305f\u3002<\/p>\n
\u3000\u30b0\u30ec\u30fc\u30c93\u4ee5\u4e0a\u306e\u8840\u5c0f\u677f\u6e1b\u5c11\u304c\u767a\u73fe\u3057\u305f37\u4eba\u3067\u306f\u3001\u30b0\u30ec\u30fc\u30c91\u4ee5\u4e0a\u306b\u6539\u5584\u3059\u308b\u306e\u306b\u8981\u3057\u305f\u5e73\u5747\u671f\u9593\u306f32\u65e5\u9593\u3060\u3063\u305f\u3002<\/p>\n
\u3000\u8a55\u4fa1\u304c\u53ef\u80fd\u3060\u3063\u305f74\u4eba\u4e2d\u3001\u5168\u5bdb\u89e3\u7387\uff08ORR\uff09\u306f58\uff05\u3001CR\u306f28\uff05\u3060\u3063\u305f\u3002FL\u306e65\u4eba\u3067\u306f\u3001ORR\u306f63\uff05\u3001CR\u306f33\uff05\u3060\u3063\u305f\u3002\u5bdb\u89e3\u304c\u5f97\u3089\u308c\u305fFL\u306e41\u4eba\u4e2d\u3001\u518d\u767a\u307e\u305f\u306f\u9032\u884c\u3092\u8a8d\u3081\u305f\u306e\u306f9\u4eba\u306e\u307f\u3060\u3063\u305f\u3002FL\u306e\u60a3\u8005\u3067\u306f\u3001\u524d\u6cbb\u7642\u306e\u30ea\u30c4\u30ad\u30b7\u30de\u30d6\u306b\u62b5\u6297\u6027\u3060\u3063\u305f\u5834\u5408\u308249\uff05\u3067\u5bdb\u89e3\u304c\u5f97\u3089\u308c\u305f\u3002<\/p>\n
\u3000\u7121\u5897\u60aa\u751f\u5b58\u671f\u9593\uff08PFS\uff09\u306e\u4e2d\u592e\u5024\u306f15.5\u30ab\u6708\u3060\u3063\u305f\u3002FL\u306e\u60a3\u8005\u3067\u306f\u300112\u30ab\u6708\u6642\u306ePFS\u7387\u306f57\uff05\u3001\u5168\u751f\u5b58\u7387\uff08OS\uff09\u306f81\uff05\u3060\u3063\u305f\u3002<\/p>\n
\u3000\u5c0f\u690b\u6c0f\u306f\u3001\u300c\u4eca\u56de\u5f97\u3089\u308c\u305f\u7d50\u679c\u306f\u3001\u3053\u3046\u3057\u305f\u5bfe\u8c61\u96c6\u56e3\u306b\u5bfe\u3059\u308bInotuzumab ozogamicin\u306e\u81e8\u5e8a\u958b\u767a\u306e\u7d99\u7d9a\u3092\u652f\u6301\u3059\u308b\u3082\u306e\u300d\u3068\u8a71\u3057\u305f\u3002<\/p>\n
\u3000Inotuzumab ozogamicin\u306b\u3064\u3044\u3066\u306f\u4e16\u754c\u30674\u4ef6\u306e\u81e8\u5e8a\u8a66\u9a13\u304c\u9032\u884c\u4e2d\u3067\u3001\u3053\u306e\u3046\u30612\u4ef6\u306b\u306f\u65e5\u672c\u3082\u53c2\u52a0\u3057\u3066\u3044\u308b\u3002<\/p>\n
\n\u4ee5\u4e0a<\/p>\n","protected":false},"excerpt":{"rendered":"
\u4eca\u5e74\u306f\u884c\u3051\u306a\u304b\u3063\u305f\u3001\u7b2c73\u56de\u65e5\u672c\u8840\u6db2\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a\u3067\u3001\u540d\u53e4\u5c4b\u7b2c\u4e8c\u8d64\u5341\u5b57\u75c5\u9662\u8840\u6db2\u30fb\u816b\u760d\u5185\u79d1\u306e\u5c0f\u690b\u7f8e\u77e5\u5247\u6c0f\u304c\u767a\u8868\u3057\u305f\u3068\u306e\u3053\u3068\u3002 FL\u518d\u767a\u60a3\u8005\u306b\u306f\u6717\u5831\u306e\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u304c\u305e\u304f\u305e\u304f\u3068\u51fa\u3066\u304d\u305d\u3046\u3067\u3059\u3002 \u3072\u3068\u3064\u51fa\u308b\u305f\u3073\u306b\u3001\u4f55\u5e74\u304b\u306e\u5ef6\u547d\u304c\u671f\u5f85\u3067\u304d\u305d\u3046\u3067\u3059\u3002
\n\u3000\u6297CD22\u6297\u4f53\u3092\u30ab\u30ea\u30b1\u30a2\u30df\u30b7\u30f3\u306b\u7d50\u5408\u3055\u305b\u305f\u88fd\u5264\u3001Inotuzumab Ozogamicin\u306f\u3001\u96e3\u6cbb\u6027\u306e\u518d\u767a\u6027\u4f4e\u60aa\u6027\u5ea6B\u7d30\u80de\u975e\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\uff08B-NHL\uff09\u60a3\u8005\u306b\u304a\u3044\u3066\u3001\u81e8\u5e8a\u7684\u306a\u6709\u52b9\u6027\u304c\u660e\u3089\u304b\u3067\u6bd2\u6027\u3082\u7ba1\u7406\u53ef\u80fd\u3067\u3042\u308b\u3053\u3068\u304c\u3001\u56fd\u969b\u7684\u306a\u591a\u65bd\u8a2d\u5171\u540c\u306e\u30d5\u30a7\u30fc\u30ba2\u8a66\u9a13\u304b\u3089\u793a\u3055\u308c\u305f\u3002<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-270","post","type-post","status-publish","format-standard","hentry","category-4"],"_links":{"self":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts\/270","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=270"}],"version-history":[{"count":0,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=\/wp\/v2\/posts\/270\/revisions"}],"wp:attachment":[{"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=270"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=270"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haruko.km2m.net\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=270"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}